AUTOPHAGY

THE MOST IMPORTANT BENEFIT OF AUTOPHAGY WILL SURPRISE YOU

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Last updated on March 12th, 2024 at 02:10 pm

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Cancer is one of the main reasons people die all over the world. In 2017, the CDC released a report saying that cancer was the second leading cause of death in the USA, following heart disease. The big question is, what can we do to keep this disease from hurting us? Autophagy is a really amazing and interesting process that has a lot of benefits. But autophagy has one benefit that stands out, and it has to do with cancer.

What Is Autophagy?

Autophagy is like a superhero inside your body, clearing out the old and broken stuff to make way for the new. It’s a fantastic process that helps keep you healthy and strong. This superhero works with tiny machines called enzymes, which are essential for various tasks in your body.

The word “autophagy” literally means “self-eating,” and here’s why. Your body has a unique system for getting rid of proteins that are no longer useful. These unwanted proteins are like old, worn-out tools that need to go. That’s where autophagy comes in.

Imagine your cells are little cleaners, and the lysosome is their trusty vacuum. Autophagy is the system that gathers all the old and broken proteins, like a diligent housekeeper. Then, it sends them to the lysosome, which acts like a recycling plant. The lysosome works its magic, breaking down these proteins into valuable goodies – free fatty acids and amino acids.

These goodies are like Lego blocks for your body. Amino acids are the building blocks your cells use to create new proteins and tissues. So, thanks to autophagy, your body transforms waste into the essential raw materials needed for growth and repair.

In simple words, autophagy is your body’s recycling hero, ensuring that nothing goes to waste and that you always have the tools you need to stay strong and healthy.

How to Trigger Autophagy

One of the best ways to make autophagy happen is by doing Intermittent fasting. When a person does intermittent fasting, a lot of amazing things happen in their bodies. It’s not just about losing weight. The loss of weight is also a great benefit. Autophagy is one of the best things about intermittent fasting, if not the best thing. After about 18 hours of not eating, the autophagy process starts.

To do intermittent fasting, you just have to give up all snacks and small meals. When you start doing intermittent fasting, you do it slowly at first. You could start by giving up snacks and eating only three meals a day. Cutting back to two meals a day or even just one when you feel good. And if you are practicing intermittent fasting for a long time, you might consider not eating for the rest of the day. This can have some pretty amazing effects on the body as a whole. I’ve found that combining intermittent fasting with the keto diet is the most effective way to do it.

There are a few more ways to start autophagy

  • Ketones
  • Hyperbaric oxygen therapy
  • Cruciferous vegetables
  • Extra virgin olive oil
  • Regular exercise
  • Sleep
  • Cold/hot therapy
  • Green tea

Some Good Things About Autophagy

  • It has the potential to decrease the risk of disease.
  • It may protect neurons and heart cells. 
  • It can help recycle protein as a way to stay alive.
  • It can help get rid of pathogens in the body. 
  • It can get rid of advanced glycated end products and amyloid plaques.

The Most Important Benefit of Autophagy

As you can see, autophagy is a very interesting process that helps the body in many ways. But out of all the health benefits of autophagy, I think the most important one is that it might help fight cancer. These amazing effects are caused by autophagy, which may be able to fix the damage in cancer cells in a way that nothing else can. Let me explain this.

Cancer Cell VS Normal Cell

In a healthy cell without cancer, a crucial process called mitochondrial respiration takes place. But what does that mean in simple terms? Well, it’s like a machine that turns fuel into ATP, which is your body’s energy currency. Your body can use glucose as its fuel, which gets burned with the help of oxygen.

The energy generators in your body are called mitochondria. So, when we discuss mitochondrial respiration, we’re talking about these energy generators and how they use oxygen (basically, your breathing). For a regular cell, oxygen is a must to produce energy.

Now, the way a cancer cell gets its energy is different. It has a problem with how it breathes, and this can’t be fixed easily. When the mitochondrial respiration system is damaged in a cancer cell, it starts using an old, alternative pathway to survive. This old process lets the cell break down glucose into energy without needing any oxygen. Unlike normal cells, cancer cells can ferment glucose to make energy, and oxygen isn’t a part of this process.

In simple terms, while healthy cells use oxygen to produce energy, cancer cells resort to a different method, fermenting glucose without oxygen. Understanding these differences is crucial in the ongoing fight against cancer and finding effective treatments.

WHAT IS A PET SCAN

A PET scan is one of the ways doctors check to see if someone has cancer. A PET scan measures extreme glucose consumption. Cancer cells love glucose. They have a huge need for glucose. Cancer cells take in more glucose than other cells do. They sometimes even starve the normal cells. If someone has cancer and knows this, why would they want to eat a lot of glucose or sugar?

Now, you might be thinking about how this damage got into the part of the mitochondria that does the breathing in the first place. Well, one thing that makes mitochondria very special is that it has their DNA. My guess is that the damage to the breathing system is related to the damage to the DNA. The DNA in the mitochondria is much more likely to change or become mutated because it is not as well protected as the DNA in the nucleus of the cell. I think this system gets broken because it isn’t safe. Your body can’t get cancer unless the breathing part of the mitochondria is damaged.

Incredible Anti-Cancer Effects

Here is where autophagy’s amazing potential to fight cancer comes in. Autophagy might actually be able to fix the damage in the mitochondria. Enzymes are the machines that make proteins in the mitochondria. Autophagy could fix the damaged proteins in the mitochondria that cause the cells to switch to glucose fermentation. 

Summary of The Most Important Benefit of Autophagy

Autophagy helps people stay young. It helps keep the body healthy. It might lower the chance of getting an infection or getting sick, and it does a lot of other things as well. But the most significant benefit of autophagy is that it might help the body fight cancer.

One of the best ways to start autophagy is to fast for short periods. Intermittent fasting has a lot of great health benefits all on its own. Take advantage of all that autophagy has to offer to keep your body healthy and safe.

Ali webster author of syktohealth
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Ali Webster is a seasoned researcher, communicator, and Registered Dietitian with a diverse background encompassing government, nonprofits, academia, and health care. The core belief is that science should be made accessible, understandable, and relevant to all individuals, driving the motivation behind their work. Proficient in conducting and interpreting research to shape nutrition policy decisions, the individual also excels in nutrition and health communication, consumer research survey development and implementation, and clinical nutrition. Holding a Doctorate of Philosophy with a focus on Nutrition and Epidemiology from the University of Minnesota, their dietetic internship emphasized medical nutrition therapy.


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